Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition

Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition

Multidrug resistance (MDR) is regarded as one of the bottlenecks of successful clinical treatment for numerous chemotherapeutic agents. Multiple key regulators are alleged to be responsible for MDR and making the treatment regimens ineffective. In this review, we discuss MDR in relation to P-glycopr...

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Bibliographic Details
Main Authors: Saikat Dewanjee, Tarun K. Dua, Niloy Bhattacharjee, Anup Das, Moumita Gangopadhyay, Ritu Khanra, Swarnalata Joardar, Muhammad Riaz, Vincenzo De Feo, Muhammad Zia-Ul-Haq
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
P-glycoprotein (P-gp)
multi drug resistance (MDR)
ABC transporters
P-gp inhibitors
chemotherapy
xenobiotics
Online Access:http://www.mdpi.com/1420-3049/22/6/871

Internet

http://www.mdpi.com/1420-3049/22/6/871

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