Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration.

The zinc transporter ZIP4 (Slc39a4) is important for proper mammalian development and is an essential gene in mice. Recent studies suggest that this gene may also play a role in pancreatic cancer.Herein, we present evidence that this essential zinc transporter is expressed in hepatocellular carcinom...

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Bibliographic Details
Main Authors: Benjamin P Weaver, Yuxia Zhang, Stephen Hiscox, Grace L Guo, Udayan Apte, Kathryn M Taylor, Christian T Sheline, Li Wang, Glen K Andrews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2950147?pdf=render