Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions

Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions

Both genetic and environmental interactions affect systemic lupus erythematosus (SLE) development and pathogenesis. One known genetic factor associated with lupus is a haplotype of the interferon regulatory factor 5 (IRF5) gene. Analysis of global gene expression microarray data using gene set enric...

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Bibliographic Details
Main Authors: Joel M. Guthridge, Daniel N. Clark, Amanda Templeton, Nicolas Dominguez, Rufei Lu, Gabriel S. Vidal, Jennifer A. Kelly, Kenneth M. Kauffman, John B. Harley, Patrick M. Gaffney, Judith A. James, Brian D. Poole
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/594056

Internet

http://dx.doi.org/10.1155/2012/594056

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