Loss of muscleblind-like 1 promotes invasive mesenchyme formation in endocardial cushions by stimulating autocrine TGFβ3
<p>Abstract</p> <p>Background</p> <p>Valvulogenesis and septation in the developing heart depend on the formation and remodeling of endocardial cushions in the atrioventricular canal (AVC) and outflow tract (OFT). These cushions are invaded by a subpopulation of endocar...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-08-01
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Series: | BMC Developmental Biology |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-213X/12/22 |