Haloperidol Attenuates Lung Endothelial Cell Permeability In Vitro and In Vivo

Haloperidol Attenuates Lung Endothelial Cell Permeability In Vitro and In Vivo

We previously reported that claudin-5, a tight junctional protein, mediates lung vascular permeability in a murine model of acute lung injury (ALI) induced by lipopolysaccharide (LPS). Recently, it has been reported that haloperidol, an antipsychotic medication, dose-dependently increases expression...

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Bibliographic Details
Main Authors: Marco A. Colamonici, Yulia Epshtein, Weiguo Chen, Jeffrey R. Jacobson
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
haloperidol
claudin-5
endothelial cells
vascular permeability
acute lung injury
Online Access:https://www.mdpi.com/2073-4409/10/9/2186

Internet

https://www.mdpi.com/2073-4409/10/9/2186

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