Dissolution Enhancement and Controlled Release of Paclitaxel Drug via a Hybrid Nanocarrier Based on mPEG-PCL Amphiphilic Copolymer and Fe-BTC Porous Metal-Organic Framework

Dissolution Enhancement and Controlled Release of Paclitaxel Drug via a Hybrid Nanocarrier Based on mPEG-PCL Amphiphilic Copolymer and Fe-BTC Porous Metal-Organic Framework

In the present work, the porous metal-organic framework (MOF) Basolite<sup>®</sup>F300 (Fe-BTC) was tested as a potential drug-releasing depot to enhance the solubility of the anticancer drug paclitaxel (PTX) and to prepare controlled release formulations after its encapsulation in amphi...

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Bibliographic Details
Main Authors: Nikolaos D. Bikiaris, Nina Maria Ainali, Evi Christodoulou, Margaritis Kostoglou, Thomas Kehagias, Emilia Papasouli, Emmanuel N. Koukaras, Stavroula G. Nanaki
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Nanomaterials
Subjects:
mPEG-PCL copolymer
Fe-BTC
metal-organic framework
paclitaxel
nanoparticles
dissolution enhancement
Online Access:https://www.mdpi.com/2079-4991/10/12/2490

Internet

https://www.mdpi.com/2079-4991/10/12/2490

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