A new approach for the assessment of the toxicity of polyphenol-rich compounds with the use of high content screening analysis.

The toxicity of in vitro tested compounds is usually evaluated based on AC50 values calculated from dose-response curves. However, there is a large group of compounds for which a standard four-parametric sigmoid curve fitting may be inappropriate for estimating AC50. In the present study, 22 polyphe...

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Bibliographic Details
Main Authors: Magdalena Boncler, Jacek Golanski, Magdalena Lukasiak, Malgorzata Redzynia, Jaroslaw Dastych, Cezary Watala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5491109?pdf=render