THE PROGNOSTIC SIGNIFICANCE OF TET2 SINGLE NUCLEOTIDE POLYMORPHISM IN EGYPTIAN CHRONIC MYELOID LEUKEMIA

THE PROGNOSTIC SIGNIFICANCE OF TET2 SINGLE NUCLEOTIDE POLYMORPHISM IN EGYPTIAN CHRONIC MYELOID LEUKEMIA

Background: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm. The pathogenesis of CML is based on the oncoprotein termed BCR‐ABL1. TET2 initiates DNA demethylation and is frequently mutated in hematological malignancies including CML.(1) The relation between TET2 acquisition and CML...

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Bibliographic Details
Main Authors: Enas A Dammag, Nahla A.M. Hamed, Professor, Nabil A El Halawani, Professor, Heba S Kassem, Professor, Mona W Ayad, Professor
Format: Article
Language:English
Published: PAGEPress Publications 2020-01-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Chronic Myeloid Leukemia
Ten Eleven Translocation 2 gene
Online Access:http://mjhid.org/index.php/mjhid/article/view/3993

Internet

http://mjhid.org/index.php/mjhid/article/view/3993

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