Thalidomide attenuates the hyporesponsiveness of isolated atria to chronotropic stimulation in BDL rats: The involvement of TNF-α, IL-6 inhibition, and SOCS1 activation

Thalidomide attenuates the hyporesponsiveness of isolated atria to chronotropic stimulation in BDL rats: The involvement of TNF-α, IL-6 inhibition, and SOCS1 activation

<em><strong>Objective(s):</strong></em> Cirrhotic cardiomyopathy is a complication of uncured cirrhosis which is associated with hyporesponsiveness of the heart to sympathetic stimulation. The enhancement of portal pressure, nitric oxide (NO) level, pro-inflammatory mediators...

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Bibliographic Details
Main Authors: Ali Hosseini-chegeni, farahnaz Jazaeri, Aliakbar Yousefi-Ahmadipour, Mansour Heidari, Alireza Abdollahi, Ahmad Reza Dehpour
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cirrhotic cardiomyopathy
il-6
socs1
thalidomide
tnf-α
Online Access:http://ijbms.mums.ac.ir/article_13886_0783b44401da8d35992d9e5ddb361bea.pdf

Internet

http://ijbms.mums.ac.ir/article_13886_0783b44401da8d35992d9e5ddb361bea.pdf

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