Calpain activity is essential in skin wound healing and contributes to scar formation.

Wound healing is a multistep phenomenon that relies on complex interactions between various cell types. Calpains are ubiquitously expressed proteases regulating several processes including cellular adhesion and motility as well as inflammation and angiogenesis. Calpains can be targeted by inhibitors...

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Bibliographic Details
Main Authors: Dany Nassar, Emmanuel Letavernier, Laurent Baud, Selim Aractingi, Kiarash Khosrotehrani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3353912?pdf=render