Role of tau N-terminal motif in the secretion of human tau by End Binding proteins.

For unknown reasons, humans appear to be particular susceptible to developing tau pathology leading to neurodegeneration. Transgenic mice are still undoubtedly the most popular and extensively used animal models for studying Alzheimer's disease and other tauopathies. While these murine models g...

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Bibliographic Details
Main Authors: C Laura Sayas, Miguel Medina, Raquel Cuadros, Ivanna Ollá, Esther García, Mar Pérez, Isidro Ferrer, Félix Hernández, Jesús Avila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210864