A Computational Approach for Identifying Synergistic Drug Combinations.

A promising alternative to address the problem of acquired drug resistance is to rely on combination therapies. Identification of the right combinations is often accomplished through trial and error, a labor and resource intensive process whose scale quickly escalates as more drugs can be combined....

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Bibliographic Details
Main Authors: Kaitlyn M Gayvert, Omar Aly, James Platt, Marcus W Bosenberg, David F Stern, Olivier Elemento
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5234777?pdf=render