MEIS2 regulates endothelial to hematopoietic transition of human embryonic stem cells by targeting TAL1

MEIS2 regulates endothelial to hematopoietic transition of human embryonic stem cells by targeting TAL1

Abstract Background Despite considerable progress in the development of methods for hematopoietic differentiation, efficient generation of transplantable hematopoietic stem cells (HSCs) and other genuine functional blood cells from human embryonic stem cells (hESCs) is still unsuccessful. Therefore,...

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Bibliographic Details
Main Authors: Mengge Wang, Hongtao Wang, Yuqi Wen, Xiaoyuan Chen, Xin Liu, Jie Gao, Pei Su, Yuanfu Xu, Wen Zhou, Lihong Shi, Jiaxi Zhou
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Stem Cell Research & Therapy
Subjects:
MEIS2
Hematopoiesis
EHT
Online Access:http://link.springer.com/article/10.1186/s13287-018-1074-z

Internet

http://link.springer.com/article/10.1186/s13287-018-1074-z

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