Phoneutria nigriventer ω-Phonetoxin IIA: A new tool for anti-calcium channel autoantibody assays in Lambert–Eaton myasthenic syndrome
Lambert–Eaton myasthenic syndrome (LEMS) is a neurological autoimmune disease in which downregulation of voltage-gated calcium channels (VGCCs) leads to reduced acetylcholine release from motoneuron terminals. 70% of cases are paraneoplastic and rapid diagnosis of LEMS can result in early detection...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2006-04-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999610500272X |