Phoneutria nigriventer ω-Phonetoxin IIA: A new tool for anti-calcium channel autoantibody assays in Lambert–Eaton myasthenic syndrome

Phoneutria nigriventer ω-Phonetoxin IIA: A new tool for anti-calcium channel autoantibody assays in Lambert–Eaton myasthenic syndrome

Lambert–Eaton myasthenic syndrome (LEMS) is a neurological autoimmune disease in which downregulation of voltage-gated calcium channels (VGCCs) leads to reduced acetylcholine release from motoneuron terminals. 70% of cases are paraneoplastic and rapid diagnosis of LEMS can result in early detection...

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Bibliographic Details
Main Authors: Nicole Martin-Moutot, Luc de Haro, Raquel Gouvea Dos Santos, Yasuo Mori, Michael Seagar
Format: Article
Language:English
Published: Elsevier 2006-04-01
Series:Neurobiology of Disease
Subjects:
Lambert–Eaton myasthenic syndrome
ω-Phonetoxin IIA
Calcium channel
Serological assay
Autoantibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610500272X

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http://www.sciencedirect.com/science/article/pii/S096999610500272X

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