Potential predictive value of SCN4A mutation status for immune checkpoint inhibitors in melanoma

Potential predictive value of SCN4A mutation status for immune checkpoint inhibitors in melanoma

Melanoma refers to a pigmented nevus with malignant changes. The preferred treatment for primary melanoma is surgical excision and postoperative radiotherapy, but the prognosis is poor. Immune checkpoint inhibitors (ICIs) have been remarkably successful in different types of cancers, but not all can...

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Bibliographic Details
Main Authors: Weiyin Lin, Anqi Lin, Zhefu Li, Chaozheng Zhou, Chufeng Chen, Boliang Chen, Qingwen Lyu, Jian Zhang, Peng Luo
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
SCN4A
TMB
DDR
Melanoma
Immune checkpoint inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222030826X

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http://www.sciencedirect.com/science/article/pii/S075333222030826X

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