Carvacrol and trans-Cinnamaldehyde Reduce Clostridium difficile Toxin Production and Cytotoxicity in Vitro

Carvacrol and trans-Cinnamaldehyde Reduce Clostridium difficile Toxin Production and Cytotoxicity in Vitro

Clostridium difficile is a nosocomial pathogen that causes a serious toxin-mediated enteric disease in humans. Reducing C. difficile toxin production could significantly minimize its pathogenicity and improve disease outcomes in humans. This study investigated the efficacy of two, food-grade, plant...

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Bibliographic Details
Main Authors: Shankumar Mooyottu, Anup Kollanoor-Johny, Genevieve Flock, Laurent Bouillaut, Abhinav Upadhyay, Abraham L. Sonenshein, Kumar Venkitanarayanan
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:International Journal of Molecular Sciences
Subjects:
plant compounds
Clostridium difficile
toxins
gene expression
Online Access:http://www.mdpi.com/1422-0067/15/3/4415

Internet

http://www.mdpi.com/1422-0067/15/3/4415

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