Clinical Significance of PDCD4 in Melanoma by Subcellular Expression and in Tumor-Associated Immune Cells

Clinical Significance of PDCD4 in Melanoma by Subcellular Expression and in Tumor-Associated Immune Cells

Little is known about the subcellular localization and function of programmed cell death 4 (PDCD4) in melanoma. Our past studies suggest PDCD4 interacts with Pleckstrin Homology Domain Containing A5 (PLEKHA5) to influence melanoma brain metastasis outcomes, as high intracranial PDCD4 expression lead...

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Bibliographic Details
Main Authors: Thuy T. Tran, Chetan K. Rane, Christopher R. Zito, Sarah A. Weiss, Shlomit Jessel, Liliana Lucca, Benjamin Y. Lu, Victor O. Oria, Adebowale Adeniran, Veronica L. Chiang, Sacit Bulent Omay, David A. Hafler, Harriet M. Kluger, Lucia B. Jilaveanu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
PDCD4
brain metastasis
melanoma
PLEKHA5
tumor-infiltrating leukocytes
Online Access:https://www.mdpi.com/2072-6694/13/5/1049

Internet

https://www.mdpi.com/2072-6694/13/5/1049

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