Alternative approaches to target Myc for cancer treatment

Abstract The Myc proto-oncogene family consists of three members, C-MYC, MYCN, and MYCL, which encodes the transcription factor c-Myc (hereafter Myc), N-Myc, and L-Myc, respectively. Myc protein orchestrates diverse physiological processes, including cell proliferation, differentiation, survival, an...

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Bibliographic Details
Main Authors: Chen Wang, Jiawei Zhang, Jie Yin, Yichao Gan, Senlin Xu, Ying Gu, Wendong Huang
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00500-y