Trail (TNF-related apoptosis-inducing ligand) induces an inflammatory response in human adipocytes

Abstract High serum concentrations of TNF-related apoptosis-inducing ligand (TRAIL), a member of the tumor necrosis factor protein family, are found in patients with increased BMI and serum lipid levels. In a model of murine obesity, both the expression of TRAIL and its receptor (TRAIL-R) is elevate...

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Bibliographic Details
Main Authors: Verena Zoller, Jan-Bernd Funcke, Julian Roos, Meike Dahlhaus, Muad Abd El Hay, Karlheinz Holzmann, Ralf Marienfeld, Thomas Kietzmann, Klaus-Michael Debatin, Martin Wabitsch, Pamela Fischer-Posovszky
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05932-7