Germline Genetic Findings Which May Impact Therapeutic Decisions in Families with a Presumed Predisposition for Hereditary Breast and Ovarian Cancer

Germline Genetic Findings Which May Impact Therapeutic Decisions in Families with a Presumed Predisposition for Hereditary Breast and Ovarian Cancer

In this study, we aim to gain insight in the germline mutation spectrum of <i>ATM</i>, <i>BARD1</i>, <i>BRIP1</i>, <i>ERCC4</i>, <i>PALB2</i>, <i>RAD51C</i> and <i>RAD51D</i> in breast and ovarian cancer families fro...

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Bibliographic Details
Main Authors: Carolina Velázquez, Kim De Leeneer, Eva M. Esteban-Cardeñosa, Francisco Avila Avila Cobos, Enrique Lastra, Luis E. Abella, Virginia de la de la Cruz, Carmen D. Lobatón, Kathleen B. Claes, Mercedes Durán, Mar Infante
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
HBOC
genetic testing
variant prioritisation
therapeutic selection
family history
clinical guidelines
Online Access:https://www.mdpi.com/2072-6694/12/8/2151

Internet

https://www.mdpi.com/2072-6694/12/8/2151

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