Effects of iron overload on the bone marrow microenvironment in mice.

Effects of iron overload on the bone marrow microenvironment in mice.

Using a mouse model, Iron Overload (IO) induced bone marrow microenvironment injury was investigated, focusing on the involvement of reactive oxygen species (ROS).Mice were intraperitoneally injected with iron dextran (12.5, 25, or 50 mg) every three days for two, four, and six week durations. Defer...

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Bibliographic Details
Main Authors: Yuchen Zhang, Wenjing Zhai, Mingfeng Zhao, Deguan Li, Xiao Chai, Xiaoli Cao, Juanxia Meng, Jie Chen, Xia Xiao, Qing Li, Juan Mu, Jichun Shen, Aimin Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4361683?pdf=render

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http://europepmc.org/articles/PMC4361683?pdf=render

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