Bufei Jianpi Formula Improves Mitochondrial Function and Suppresses Mitophagy in Skeletal Muscle via the Adenosine Monophosphate-Activated Protein Kinase Pathway in Chronic Obstructive Pulmonary Disease

Bufei Jianpi Formula Improves Mitochondrial Function and Suppresses Mitophagy in Skeletal Muscle via the Adenosine Monophosphate-Activated Protein Kinase Pathway in Chronic Obstructive Pulmonary Disease

Skeletal muscle dysfunction, a striking systemic comorbidity of chronic obstructive pulmonary disease (COPD), is associated with declines in activities of daily living, reductions in health status and prognosis, and increases in mortality. Bufei Jianpi formula (BJF), a traditional Chinese herbal for...

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Bibliographic Details
Main Authors: Jing Mao, Ya Li, Suxiang Feng, Xuefang Liu, Yange Tian, Qingqing Bian, Junzi Li, Yuanyuan Hu, Lanxi Zhang, Huige Ji, Suyun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
mitophagy
mitochondrial biogenesis
chronic obstructive pulmonary disease
Bufei Jianpi formula
skeletal muscle dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.587176/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.587176/full

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