High-Fat Breakfast Increases Bioavailability of Albendazole Compared to Low-Fat Breakfast: Single-Dose Study in Healthy Subjects

High-Fat Breakfast Increases Bioavailability of Albendazole Compared to Low-Fat Breakfast: Single-Dose Study in Healthy Subjects

Purpose: Albendazole is a benzimidazole carbamate drug with anthelmintic and antiprotozoal activity against intestinal and tissue parasites. It has been described that the administration with meals increases albendazole absorption. Our aim was to compare the systemic exposure in healthy volunteers o...

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Bibliographic Details
Main Authors: Dolores Ochoa, Miriam Saiz-Rodríguez, Esperanza González-Rojano, Manuel Román, Sergio Sánchez-Rojas, Aneta Wojnicz, Ana Ruiz-Nuño, Alfredo García-Arieta, Francisco Abad-Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
albendazole
breakfast
bioavailability
healthy subjects
pharmacokinetic
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.664465/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.664465/full

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