Local adaptation and archaic introgression shape global diversity at human structural variant loci

Local adaptation and archaic introgression shape global diversity at human structural variant loci

Large genomic insertions and deletions are a potent source of functional variation, but are challenging to resolve with short-read sequencing, limiting knowledge of the role of such structural variants (SVs) in human evolution. Here, we used a graph-based method to genotype long-read-discovered SVs...

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Bibliographic Details
Main Authors: Stephanie M Yan, Rachel M Sherman, Dylan J Taylor, Divya R Nair, Andrew N Bortvin, Michael C Schatz, Rajiv C McCoy
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
positive selection
immunoglobulin
neanderthal
insertion
deletion
eQTL
Online Access:https://elifesciences.org/articles/67615

Internet

https://elifesciences.org/articles/67615

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