ORMDL proteins regulate ceramide levels during sterile inflammation

ORMDL proteins regulate ceramide levels during sterile inflammation

The bioactive sphingolipid metabolite, ceramide, regulates physiological processes important for inflammation and elevated levels of ceramide have been implicated in IL-1-mediated events. Although much has been learned about ceramide generation by activation of sphingomyelinases in response to IL-1,...

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Bibliographic Details
Main Authors: Lin Cai, Clement Oyeniran, Debolina D. Biswas, Jeremy Allegood, Sheldon Milstien, Tomasz Kordula, Michael Maceyka, Sarah Spiegel
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of Lipid Research
Subjects:
serine palmitoyltransferase
ORM-like protein
ceramide synthase
sphingolipids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352135

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http://www.sciencedirect.com/science/article/pii/S0022227520352135

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