Nerve Fibers in the Tumor Microenvironment are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer

Nerve Fibers in the Tumor Microenvironment are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer

B cells and tertiary lymphoid structures (TLS) are reported to be important in survival in cancer. Pancreatic Cancer (PDAC) is one of the most lethal cancer types, and currently, it is the seventh leading cause of cancer-related death worldwide. A better understanding of tumor biology is pivotal to...

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Bibliographic Details
Main Authors: Lara R. Heij, Xiuxiang Tan, Jakob N. Kather, Jan M. Niehues, Shivan Sivakumar, Nicole Heussen, Gregory van der Kroft, Steven W. M. Olde Damink, Sven Lang, Merel R. Aberle, Tom Luedde, Nadine T. Gaisa, Jan Bednarsch, Drolaiz H. W. Liu, Jack P. M. Cleutjens, Dominik P. Modest, Ulf P. Neumann, Georg J. Wiltberger
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Journal of Clinical Medicine
Subjects:
tumor microenvironment
machine learning
nerve fiber density
spatial arrangements
tertiary lymphoid structures
pancreatic cancer
Online Access:https://www.mdpi.com/2077-0383/10/3/490

Internet

https://www.mdpi.com/2077-0383/10/3/490

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