Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin

Zebrafish regenerate their fins via the formation of a population of progenitor cells, the blastema. Wnt/β-catenin signaling is essential for blastemal cell proliferation and patterning of the overlying epidermis. Yet, we find that β-catenin signaling is neither active in the epidermis nor the major...

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Bibliographic Details
Main Authors: Daniel Wehner, Wiebke Cizelsky, Mohankrishna Dalvoy Vasudevaro, Günes Özhan, Christa Haase, Birgit Kagermeier-Schenk, Alexander Röder, Richard I. Dorsky, Enrico Moro, Francesco Argenton, Michael Kühl, Gilbert Weidinger
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713007948