Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model

Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model

Objective: Motor neurons (MNs) die in amyotrophic lateral sclerosis (ALS), a clinically heterogeneous neurodegenerative disease of unknown etiology. In human or rodent studies, MN loss is preceded by increased excitability. As increased neuronal excitability correlates with structural changes in den...

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Bibliographic Details
Main Authors: Matthew J. Fogarty, Erica W. H. Mu, Nickolas A. Lavidis, Peter G. Noakes, Mark C. Bellingham
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Neuroscience
Subjects:
dendrite
spine density
striatum
hippocampus
hypoglossal motor neuron
trochlear motor neuron
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00609/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00609/full

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