Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Enable a Stable Non-Spilling Loading of T Cells and Their Magnetic Accumulation
T cell infiltration into a tumor is associated with a good clinical prognosis of the patient and adoptive T cell therapy can increase anti-tumor immune responses. However, immune cells are often excluded from tumor infiltration and can lack activation due to the immune-suppressive tumor microenviron...
Main Authors: | Philipp Boosz, Felix Pfister, Rene Stein, Bernhard Friedrich, Lars Fester, Julia Band, Marina Mühlberger, Eveline Schreiber, Stefan Lyer, Diana Dudziak, Christoph Alexiou, Christina Janko |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/16/4143 |
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