Generation of mutation hotspots in ageing bacterial colonies
Abstract How do ageing bacterial colonies generate adaptive mutants? Over a period of two months, we isolated on ageing colonies outgrowing mutants able to use a new carbon source, and sequenced their genomes. This allowed us to uncover exquisite details on the molecular mechanism behind their adapt...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-016-0005-4 |