Extracellular Mipp1 Activity Confers Migratory Advantage to Epithelial Cells during Collective Migration

Multiple inositol polyphosphate phosphatase (Mipp), a highly conserved but poorly understood histidine phosphatase, dephosphorylates higher-order IPs (IP4–IP6) to IP3. To gain insight into the biological roles of these enzymes, we have characterized Drosophila mipp1. mipp1 is dynamically expressed i...

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Bibliographic Details
Main Authors: Yim Ling Cheng, Deborah J. Andrew
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715012796