RFCell: A Gene Selection Approach for scRNA-seq Clustering Based on Permutation and Random Forest

RFCell: A Gene Selection Approach for scRNA-seq Clustering Based on Permutation and Random Forest

In recent years, the application of single cell RNA-seq (scRNA-seq) has become more and more popular in fields such as biology and medical research. Analyzing scRNA-seq data can discover complex cell populations and infer single-cell trajectories in cell development. Clustering is one of the most im...

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Bibliographic Details
Main Authors: Yuan Zhao, Zhao-Yu Fang, Cui-Xiang Lin, Chao Deng, Yun-Pei Xu, Hong-Dong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
single-cell RNA sequencing
gene selection
permutation
random forest
clustering
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.665843/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.665843/full

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