Synthesis, characterization and biological evaluation of N-Mannich base derivatives of 2-phenyl-2-imidazoline as potential antioxidants, enzyme inhibitors, antimicrobials, cytotoxic and anti-inflammatory agents

A series of N-Mannich base derivatives of 2-phenyl-2-imidazoline with substituted amines (1–13) were designed, synthesized, and characterized by spectroanalytical techniques. The newly synthesized compounds (SP1-SP13) were evaluated biologically for their antioxidant, α-amylase enzyme inhibition, an...

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Bibliographic Details
Main Authors: Samra Farooq, Ihsan-Ul Haq, Naseem Ullah
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221000654