Colocalization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis

Stearoyl-coenzyme A desaturase (SCD) is an endoplasmic reticulum (ER) protein that catalyzes the Δ9-cis desaturation of saturated fatty acids. Mice with targeted disruption in SCD1 (Scd1−/−) have significant reduction in the tissue content of triglycerides, suggesting that monounsaturated fatty acid...

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Bibliographic Details
Main Authors: Weng Chi Man, Makoto Miyazaki, Kiki Chu, James Ntambi
Format: Article
Language:English
Published: Elsevier 2006-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434595