The cholinergic system in subtypes of Alzheimer’s disease: an in vivo longitudinal MRI study

The cholinergic system in subtypes of Alzheimer’s disease: an in vivo longitudinal MRI study

Abstract Background The heterogeneity within Alzheimer’s disease (AD) seriously challenges the development of disease-modifying treatments. We investigated volume of the basal forebrain, hippocampus, and precuneus in atrophy subtypes of AD and explored the relevance of subtype stratification in a sm...

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Main Authors: Alejandra Machado, Daniel Ferreira, Michel J. Grothe, Helga Eyjolfsdottir, Per M. Almqvist, Lena Cavallin, Göran Lind, Bengt Linderoth, Åke Seiger, Stefan Teipel, Lars U. Wahlberg, Lars-Olof Wahlund, Eric Westman, Maria Eriksdotter, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Alzheimer’s Research & Therapy
Subjects:
Basal forebrain
Alzheimer’s disease
Heterogeneity
Subtypes
Structural MRI
Nerve growth factor
Online Access:http://link.springer.com/article/10.1186/s13195-020-00620-7

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http://link.springer.com/article/10.1186/s13195-020-00620-7

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