Type II Collagen Sponges Facilitate Tendon Stem/Progenitor Cells to Adopt More Chondrogenic Phenotypes and Promote the Regeneration of Fibrocartilage-Like Tissues in a Rabbit Partial Patellectomy Model

Type II Collagen Sponges Facilitate Tendon Stem/Progenitor Cells to Adopt More Chondrogenic Phenotypes and Promote the Regeneration of Fibrocartilage-Like Tissues in a Rabbit Partial Patellectomy Model

ObjectiveFibrocartilage transition zone (FC) is difficult to regenerate after surgical re-attachment of tendon to bone. Here, we investigated whether type II collagen-sponges (CII-sponges) facilitated tendon stem/progenitor cells (TSPCs) to adopt chondrogenic phenotypes and further observed if this...

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Bibliographic Details
Main Authors: Wen Wang, Shengnan Qin, Peiliang He, Wei Mao, Liang Chen, Xing Hua, Jinli Zhang, Xifeng Xiong, Zhihe Liu, Pengzhen Wang, Qingqi Meng, Fei Dong, Aiguo Li, Honghui Chen, Jiake Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tendon stem and progenitor cells
type II collagen sponges
fibrocartilage transition zones
bone tendon junction
chondrogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.682719/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.682719/full

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