Pharmacokinetic optimisation of beta-lactams for the treatment of ventilator-associated pneumonia

Rational therapy of ventilator-associated pneumonia requires choosing the right drug at the right dose. The choice of dose depends on the microbiological goal, the range of minimum inhibitory concentrations (MICs) for likely pathogens, the extent of the drug's protein binding and, in humans, ph...

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Bibliographic Details
Main Author: G. L. Drusano
Format: Article
Language:English
Published: European Respiratory Society 2007-08-01
Series:European Respiratory Review
Subjects:
Online Access:http://err.ersjournals.com/cgi/content/full/16/103/45