Postoperative Administration of the Acetylcholinesterase Inhibitor, Donepezil, Interferes with Bone Healing and Implant Osseointegration in A Rat Model

Postoperative Administration of the Acetylcholinesterase Inhibitor, Donepezil, Interferes with Bone Healing and Implant Osseointegration in A Rat Model

Donepezil is an acetylcholinesterase inhibitor commonly used to treat mild to moderate Alzheimer’s disease. Its use has been associated with increased bone mass in humans and animals. However, the effect of postoperative administration of donepezil on bone healing remains unknown. Therefore, this st...

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Bibliographic Details
Main Authors: Faez Saleh Al-Hamed, Ola M. Maria, Jeff Phan, Ahmed Al Subaie, Qiman Gao, Alaa Mansour, Lina Abu Nada, Imane Boukhatem, Osama A. Elkashty, Simon D. Tran, Marie Lordkipanidzé, Zahi Badran, Faleh Tamimi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
acetylcholinesterase inhibitors
bone healing
osseointegration
donepezil
hemostasis
Online Access:https://www.mdpi.com/2218-273X/10/9/1318

Internet

https://www.mdpi.com/2218-273X/10/9/1318

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