Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131

Escherichia coli ST131 is the most frequently isolated fluoroquinolone-resistant (FQR) E. coli clone worldwide and a major cause of urinary tract and bloodstream infections. Although originally identified through its association with the CTX-M-15 extended-spectrum β-lactamase resistance gene, global...

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Bibliographic Details
Main Authors: Nouri L. Ben Zakour, Areej S. Alsheikh-Hussain, Melinda M. Ashcroft, Nguyen Thi Khanh Nhu, Leah W. Roberts, Mitchell Stanton-Cook, Mark A. Schembri, Scott A. Beatson
Format: Article
Language:English
Published: American Society for Microbiology 2016-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/2/e00347-16