Beneficial autoimmunity links primary biliary cholangitis to the avoidance of cholangiocarcinoma

It has been an open conundrum why primary sclerosing cholangitis (PSC) is a major risk factor for developing cholangiocarcinoma (CAA), while primary biliary cholangitis (PBC) is not. In mouse models of PSC and PBC, it turned out that the latter condition, an autoimmune disease affecting the bile duc...

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Bibliographic Details
Main Authors: Jonathan G. Pol, Juliette Paillet, Céleste Plantureux, Guido Kroemer
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1968595