Distinct Functions for Mammalian CLASP1 and -2 During Neurite and Axon Elongation

Distinct Functions for Mammalian CLASP1 and -2 During Neurite and Axon Elongation

Mammalian cytoplasmic linker associated protein 1 and -2 (CLASP1 and -2) are microtubule (MT) plus-end tracking proteins that selectively stabilize MTs at the edge of cells and that promote MT nucleation and growth at the Golgi, thereby sustaining cell polarity. In vitro analysis has shown that CLAS...

Full description

Bibliographic Details
Main Authors: Carmen Laura Sayas, Sreya Basu, Michael van der Reijden, Eugenio Bustos-Morán, Marcia Liz, Monica Sousa, Wilfred F. J. van IJcken, Jesus Avila, Niels Galjart
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cytoskeleton
microtubules
microtubule plus-end tracking proteins
cytoplasmic linker associated proteins (CLASPs)
neuronal differentiation
axon outgrowth
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00005/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00005/full

Similar Items