Effects of activated vitamin D, alfacalcidol, and low-intensity aerobic exercise on osteopenia and muscle atrophy in type 2 diabetes mellitus model rats.

Effects of activated vitamin D, alfacalcidol, and low-intensity aerobic exercise on osteopenia and muscle atrophy in type 2 diabetes mellitus model rats.

Diabetes mellitus causes secondary osteoporosis and muscle atrophy. The ability of alfacalcidol (ALF) and exercise (Exe) to inhibit osteoporosis and muscle atrophy in type 2 diabetes mellitus (T2DM) model rats was examined. Twenty-week-old Otsuka Long-Evans Tokushima Fatty rats were randomized to AL...

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Bibliographic Details
Main Authors: Manabu Akagawa, Naohisa Miyakoshi, Yuji Kasukawa, Yuichi Ono, Yusuke Yuasa, Itsuki Nagahata, Chiaki Sato, Hiroyuki Tsuchie, Hiroyuki Nagasawa, Michio Hongo, Yoichi Shimada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6192580?pdf=render

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http://europepmc.org/articles/PMC6192580?pdf=render

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