Practical and stereoselective electrocatalytic 1,2-diamination of alkenes

Methods to prepare 1,2-diamines are desirable due the importance of these compounds as drug scaffolds and organic ligands for metals. Here, the authors report an electrochemical metal-free 1,2- diamination of aryl alkenes with sulfamides to 1,2-diamines with excellent diastereoselectivity.

Bibliographic Details
Main Authors: Chen-Yan Cai, Xiao-Min Shu, Hai-Chao Xu
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13024-5