Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome

Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome

Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss of function of the maternally inherited Ube3a neuronal protein, whose main features comprise severe intellectual disabilities and motor impairments. Previous studies with the Ube3am−/p+ mouse model of AS revealed deficits in syna...

Full description

Bibliographic Details
Main Authors: Ana Moreira-de-Sá, Francisco Q. Gonçalves, João P. Lopes, Henrique B. Silva, Ângelo R. Tomé, Rodrigo A. Cunha, Paula M. Canas
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Neurobiology of Disease
Subjects:
Adenosine A2A receptor
Angelman syndrome
Ube3a
Mouse model
Hippocampus
Synaptic plasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120304125

Internet

http://www.sciencedirect.com/science/article/pii/S0969996120304125

Similar Items