Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

<p>Abstract</p> <p>Background</p> <p>Pulmonary fibrosis (PF) is a group of devastating and largely irreversible diseases. Phosphodiesterase (PDE) 4 is involved in the processes of remodeling and inflammation, which play key role in tissue fibrosis. The aim of the study...

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Main Authors: Ghofrani Hossein A, Weissmann Norbert, Al-tamari Hamza M, Pullamsetti Soni S, Dumitrascu Rio, Udalov Sergey, Guenther Andreas, Voswinckel Robert, Seeger Werner, Grimminger Friedrich, Schermuly Ralph T
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Pulmonary Medicine
Online Access:http://www.biomedcentral.com/1471-2466/10/26