Phosphorylation-independent regulation of the diguanylate cyclase WspR.

Environmental signals that trigger bacterial pathogenesis and biofilm formation are mediated by changes in the level of cyclic dimeric guanosine monophosphate (c-di-GMP), a unique eubacterial second messenger. Tight regulation of cellular c-di-GMP concentration is governed by diguanylate cyclases an...

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Bibliographic Details
Main Authors: Nabanita De, Michelle Pirruccello, Petya Violinova Krasteva, Narae Bae, Rahul Veera Raghavan, Holger Sondermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18366254/?tool=EBI