Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell–Derived Intestinal OrganoidsSummary

Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell–Derived Intestinal OrganoidsSummary

Background and aims: The COVID-19 pandemic has spread worldwide and poses a severe health risk. While most patients present mild symptoms, descending pneumonia can lead to severe respiratory insufficiency. Up to 50% of patients show gastrointestinal symptoms like diarrhea or nausea, intriguingly ass...

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Bibliographic Details
Main Authors: Jana Krüger, Rüdiger Groß, Carina Conzelmann, Janis A. Müller, Lennart Koepke, Konstantin M.J. Sparrer, Tatjana Weil, Desiree Schütz, Thomas Seufferlein, Thomas F.E. Barth, Steffen Stenger, Sandra Heller, Jan Münch, Alexander Kleger
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
SARS-CoV-2
COVID-19
Intestinal Organoids
Remdesivir
Famotidine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X2030182X

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http://www.sciencedirect.com/science/article/pii/S2352345X2030182X

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