Spotlight on the Transglutaminase 2-Heparan Sulfate Interaction

Heparan sulfate proteoglycans (HSPGs), syndecan-4 (Sdc4) especially, have been suggested as potential partners of transglutaminase-2 (TG2) in kidney and cardiac fibrosis, metastatic cancer, neurodegeneration and coeliac disease. The proposed role for HSPGs in the trafficking of TG2 at the cell surfa...

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Bibliographic Details
Main Authors: Giulia Furini, Elisabetta A.M. Verderio
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Medical Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3271/7/1/5