Low-Grade Inflammation Is Associated with Apathy Indirectly via Deep White Matter Lesions in Community-Dwelling Older Adults: The Sefuri Study

Low-Grade Inflammation Is Associated with Apathy Indirectly via Deep White Matter Lesions in Community-Dwelling Older Adults: The Sefuri Study

Low-grade inflammation is implicated in the pathogenesis of atherosclerosis, metabolic syndrome, and apathy as a form of vascular depression. We analyzed the brain magnetic resonance imaging findings in 259 community-dwelling older adults (122 men and 137 women, with a mean age of 68.4 years). The s...

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Bibliographic Details
Main Authors: Hiroshi Yao, Yoshito Mizoguchi, Akira Monji, Yusuke Yakushiji, Yuki Takashima, Akira Uchino, Takefumi Yuzuriha, Manabu Hashimoto
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
physical activity
apathy
vascular depression
vascular cognitive impairment
white matter lesions
magnetic resonance imaging
small vessel disease
silent stroke
Online Access:https://www.mdpi.com/1422-0067/20/8/1905

Internet

https://www.mdpi.com/1422-0067/20/8/1905

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