Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions

Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions

Molecular examples of evolutionary innovation are scarce and generally involve point mutations. Innovation can occur through larger rearrangements, but here experimental data is extremely limited. Integron integrases innovated from double-strand- toward single-strand-DNA recombination through the ac...

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Bibliographic Details
Main Authors: José Antonio Escudero, Aleksandra Nivina, Harry E Kemble, Céline Loot, Olivier Tenaillon, Didier Mazel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
integron
evolution
recombination
innovation
integrase
domain acquisition
Online Access:https://elifesciences.org/articles/58061

Internet

https://elifesciences.org/articles/58061

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